The relationship between neutrophil/lymphocyte ratio and uric acid levels in multiple sclerosis patients

BACKGROUND In this study, we aimed to determine whether neutrophil / lymphocyte ratio (NLR), obtained by dividing the number of neutrophils lymphocytes, and uric acid (UA) levels in multiple sclerosis (MS) patients vary compared with healthy controls establish correlations among these changes themselves as well between such MS subtypes, immunomodulatory drug use, duration disease prognosis. METHODS 150 who presented our hospital were diagnosed volunteers retrospectively included study. EDSS score (Expanded Disability Status Scale) was used assess disability patients. RESULTS Compared volunteers, had lower UA (p < 0.001) higher NLR values = 0.02). addition, a low or those on immunomodulating drugs 0.001, p 0.04, respectively). value 0.001). There negative correlation (r ‒0.23, 0.003). Similarly, level decreased increasing ‒0.38, 0.001; r ‒0.17, 0.02, CONCLUSION Evaluating value, recognized new marker for inflammation MS, together thought be protective might more effective than evaluating parameters alone demonstrating (Tab. 4, Ref. 28). Text PDF www.elis.sk Keywords: neutrophil/lymphocyte ratio, acid, sclerosis, inflammation, Expanded Scale.